Sources of Exposure :
Description :
Sucralose is a synthetic sweetener commonly added to food. Splenda is composed of sucralose and the fillers maltodextrin and glucose. Sucralose interacts with chemosensors in the alimentary tract that play a role in sweet taste sensation and hormone secretion. We include artificial sweeteners in our ingredients of concern list, for they may appear in oral care products.
Sources of Exposure: Toothpaste, mouth wash, artificially-sweetened food and beverages
Health Impacts: Although the effect of sucralose on humans has not yet been determined, in rats, sucralose reduced the beneficial bacteria in the microbial composition of the gastrointestinal tract. Both human and rodent studies demonstrated that sucralose may alter glucose, insulin, and glucagon-like peptide 1 (GLP-1) levels.
Health Concerns
Contaminants:
Banned/restricted lists:
Schiffman, S.S. et al., 2013Abou-Donia, M.B. et al., 2013