Polypropylene Glycol

Synonyms: PPG

CAS Number: 25322-69-4

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Personal care

Industrial uses

Description:

Polypropylene glycols are synthetic polyether polymers. They are used in personal care products to soften skin and stabilize product texture by promoting ingredient blending. PPGs are propoxylated chemicals, and contamination with residual 1,4-dioxane is possible. They often are listed as ingredients with PPG followed by a number, indicating the average molecular weight (ex PPG-200). They are penetration enhancers, allowing other ingredients to be absorbed more easily into the skin. PPGs are also used as an additive in many industrial applications.

Health concerns:

Irritant

May cause skin, eye, or respiratory irritation.

Contaminants:

1
4-dioxane

References

US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.