1,2-Dichloropropane
CAS Number: 78-87-5
Sources of exposure:
Historical paint strippers, industrial degreasers, chemical manufacturing, contaminated groundwater, and industrial emissions
Description:
1,2-Dichloropropane is a volatile chlorinated organic compound historically used as an industrial solvent and in certain cleaning and paint-removal products. It is also used as a chemical intermediate in manufacturing. Exposure may occur through inhalation of contaminated air, occupational handling, or contaminated groundwater.
Health concerns:
Cancer
Known or suspected to increase cancer risk in humans.
Developmental Toxicity
May impact fetal development and birth outcomes.
Genotoxicity
May cause mutations or damage DNA in cells.
Neurotoxicity
May impact brain function or development.
Respiratory Toxicity & Asthmagens
May damage the lungs or trigger asthma.
Ecotoxicity
May be toxic to ecosystems and wildlife.
Banned/restricted lists:
- California Proposition 65 - OEHHA - cancer
- EU Cosmetics Regulation Annex II - Prohibited
References
- US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox). California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.