Arsenic Pentoxide

CAS Number: 1303-28-2

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
65

Sources of exposure:

Industrial uses

Historical arsenical pesticide and wood-preservative manufacturing, industrial chemical production, contaminated soil, water, and hazardous waste sites

Description:

Arsenic pentoxide is an inorganic arsenic compound containing arsenic in its pentavalent oxidation state. It has been used in chemical manufacturing and historically in processes associated with arsenical pesticides and wood preservatives. Exposure is primarily associated with occupational handling or environmental contamination from industrial activities and historical arsenic use.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Genotoxicity

May cause mutations or damage DNA in cells.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • EU REACH Annex XIV - Authorisation List - Subject to authorisation
  • EU REACH Candidate List (SVHC) - Candidate list
  • REACH Annex XVII - Restrictions - Restricted under specified conditions

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).

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Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.