Benzyl Nicotinate

CAS Number: 94-44-0

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
88

Sources of exposure:

Personal care

OTC dermal products

Description:

Benzyl nicotinate is an aromatic ester of niacin (vitamin B3) known for its vasodilating properties. It is used in some topical over-the-counter formulations and personal care products to increase local blood flow, producing a warming sensation and transient skin redness.

Health concerns:

Genotoxicity

May cause mutations or damage DNA in cells.

Irritant

May cause skin, eye, or respiratory irritation.

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
  2. US National Library of Medicine. PubChem database.

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Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.

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