Cyclohexasiloxane (D6)

Synonyms: Dodecamethylcyclohexasiloxane

CAS Number: 540-97-6

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

personal care

industrial use

Description:

Cyclohexasiloxane is a cyclic silicone compound. It is used in cosmetics and personal care products to improve skin feel, enhance spreadability, and provide a smooth texture.

Health concerns:

Endocrine Disruption

May alter hormone function and contribute to chronic diseases and disorders.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Organ System Toxicity

May cause organ damage and disease.

Banned/restricted lists:

European Commission Annex XVII restricted substances under REACH. REACH Substance of Very High Concern (SVHC)

References

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.