D&C Yellow No. 8

Synonyms: CI 45350 - Fluorescein sodium (sodium salt), Uranine

CAS Number: 518-47-8

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Personal care

Medications

Medical imaging

Description:

D&C Yellow No. 8 is a fluorescent synthetic dye used primarily in pharmaceuticals and cosmetics. It is also widely used as a tracer dye in medical diagnostics and environmental studies due to its strong fluorescence.

Health concerns:

Genotoxicity

May cause mutations or damage DNA in cells.

Irritant

May cause skin, eye, or respiratory irritation.

Contaminants:

PAHs

Banned/restricted lists:

European Commission Annex IV colorants allowed in cosmetic products.

References

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.