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Dibutyl Phthalate (DBP)

CAS Number: 84-74-2

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
39

Sources of exposure:

personal care
cleaning products and household care
medication
industrial uses

Plastic, construction and building materials

Description:

Dibutyl phthalate (DBP) is a phthalate ester used as a plasticizer. It may be used in products such as nail polish and can also be used as a solvent or component in fragrance mixtures. It may also be used in some pharmaceutical coatings, including certain extended-release formulations.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Endocrine Disruption

May alter hormone function and contribute to chronic diseases and disorders.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Developmental Toxicity

May impact fetal development and birth outcomes.

Immunotoxicity & Allergens

May impact immune system function or cause allergic reactions.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • European Commission Annex II prohibited substances. European Commission Annex VII substances restricted under REACH. 16 CFR Part 1307 – Prohibition of children’s toys and child care articles containing specified phthalates. REACH Substance of Very High Concern (SVHC)

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
  2. California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.

For more information on our scoring methodology visit this page.