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Diisononyl Phthalate (DINP)

CAS Number: 28553-12-0

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
26

Sources of exposure:

personal care
cleaning products and household care

Plastic, vinyl flooring, PVC pipes, home goods, paints and lacquers, sealants, adhesives

Description:

Diisononyl phthalate (DINP) is a phthalate plasticizer used to make plastics more flexible and durable. It is widely used in plastic products and may also be used in fragrance. DINP is present in house dust and regularly cleaning with a damp cloth and wet mopping will help to lessen exposure. There are restrictions on DINP levels in children’s toys and related products and food packaging.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Endocrine Disruption

May alter hormone function and contribute to chronic diseases and disorders.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Developmental Toxicity

May impact fetal development and birth outcomes.

Immunotoxicity & Allergens

May impact immune system function or cause allergic reactions.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • European Commission Annex VII substances restricted under REACH. 16 CFR Part 1307 – Prohibition of children’s toys and child care articles containing specified phthalates. Available at https://www.ecfr.gov/current/title-16/chapter-II/subchapter-B/part-1307.

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
  2. California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.

For more information on our scoring methodology visit this page.