Dimethyl Isosorbide

CAS Number: 5306-85-4

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Personal care

Medications

Description:

Dimethyl isosorbide is a solvent derived from isosorbide, which is produced from glucose. It is used in personal care products to enhance the delivery and penetration of active ingredients, particularly in serums and topical treatments. It is considered bio-based but is chemically processed for commercial use.

Health concerns:

Low Health Concerns

Current research suggests ingredient may be safe for use.

References

US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).

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We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.