Dinoseb
Synonyms: 6-sec-butyl-24-dinitrophenol
CAS Number: 88-85-7
Sources of exposure:
Historical agricultural herbicides, contaminated agricultural soil, former pesticide storage or disposal sites, and environmental residues
Description:
Dinoseb is a dinitrophenol compound historically used as an herbicide and crop desiccant. Its agricultural use has been prohibited in the United States for decades because of health concerns. Current exposure is more likely associated with contaminated soil, water, or sites affected by historical pesticide use than with newly treated crops.
Health concerns:
Cancer
Known or suspected to increase cancer risk in humans.
Reproductive Toxicity
May alter hormone function and harm reproduction.
Developmental Toxicity
May impact fetal development and birth outcomes.
Genotoxicity
May cause mutations or damage DNA in cells.
Immunotoxicity & Allergens
May impact immune system function or cause allergic reactions.
Irritant
May cause skin, eye, or respiratory irritation.
Ecotoxicity
May be toxic to ecosystems and wildlife.
Banned/restricted lists:
- California Proposition 65 - OEHHA - developmental
- male
- EU Cosmetics Regulation Annex II - Prohibited
- EU REACH Candidate List (SVHC) - Candidate list
- Rotterdam Convention - Annex III - Prior Informed Consent (PIC) - Pesticide
References
- US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
- US National Library of Medicine. PubChem database.