Dioctyl Phthalate

Synonyms: Di-n-octyl phthalate, DNOP

CAS Number: 117-84-0

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
32

Sources of exposure:

Industrial uses

Flexible plastics, vinyl flooring, adhesives, packaging materials, household dust

Description:

Dioctyl phthalate is a plasticizer used to improve the flexibility and durability of plastic materials. It has been used in vinyl products, flooring, adhesives, and packaging materials. Consumer exposure may occur through contact with products containing the chemical or through household dust.

Health concerns:

Endocrine Disruption

May alter hormone function and contribute to chronic diseases and disorders.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Developmental Toxicity

May impact fetal development and birth outcomes.

Genotoxicity

May cause mutations or damage DNA in cells.

Organ System Toxicity

May cause organ damage and disease.

Immunotoxicity & Allergens

May impact immune system function or cause allergic reactions.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Banned/restricted lists:

  • REACH Annex XVII - Restrictions - Restricted under specified conditions

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox). California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.