Dioxins

Synonyms: Polychlorinated dibenzo-p-dioxins, PCDDs, Chlorinated dioxins

Sources of exposure:

Food

Animal-derived foods, contaminated soil and sediments, industrial emissions, combustion-related air pollution, occupational exposure

Description:

Dioxins are a group of persistent environmental pollutants that commonly refers to polychlorinated dibenzo-p-dioxins (PCDDs) and, more broadly, to dioxin-like compounds including polychlorinated dibenzofurans (PCDFs) and certain polychlorinated biphenyls (PCBs). These compounds are primarily formed unintentionally during combustion and certain industrial processes. They can persist in the environment, accumulate in fatty tissues, and become concentrated in food chains. Human exposure occurs predominantly through contaminated food, particularly meat, dairy products, fish, and other animal-derived foods. Individual compounds vary substantially in toxicity, and dioxin-like compounds are often evaluated using toxic equivalency factors (TEFs) to account for differences in their relative potency. PCDDs and PCDFs are addressed under Annex C of the Stockholm Convention as unintentionally produced persistent organic pollutants. Examples include 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other polychlorinated dibenzo-p-dioxin congeners. Dioxins are regulated under Annex C of the Stockholm Convention on Persistent Organic Pollutants, which requires measures to reduce their unintentional release into the environment. They are also covered under the European Union's Persistent Organic Pollutants Regulation (EU) 2019/1021, which establishes requirements for reducing releases and managing waste containing these compounds.

Health concerns:

No specific health concerns have been flagged for this chemical.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.