Ethoxydiglycol

CAS Number: 111-90-0

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Personal care

Medications

Description:

Ethoxydiglycol is a glycol ether used as a solvent and penetration enhancer in personal care and pharmaceutical formulations. It helps dissolve ingredients and improve their delivery in skincare products, hair care products, and topical treatments. As an ethoxylated compound, it may contain trace impurities such as 1,4-dioxane depending on manufacturing processes.

Health concerns:

Genotoxicity

May cause mutations or damage DNA in cells.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Contaminants:

1
4-dioxane

Banned/restricted lists:

EU Cosmetics Regulation Annex III - Restricted

References

US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox). California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.

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We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.