Ethylene Glycol

CAS Number: 107-21-1

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
48

Sources of exposure:

Industrial uses

Automotive antifreeze, engine coolants, deicing fluids, brake fluids, inks

Description:

Ethylene glycol is a synthetic, water-soluble liquid commonly used in antifreeze and engine coolants because it lowers the freezing point of water. It is also used in deicing solutions and the manufacture of polyester materials. Consumer exposure may occur through handling automotive products, spills, or accidental ingestion.

Health concerns:

Developmental Toxicity

May impact fetal development and birth outcomes.

Neurotoxicity

May impact brain function or development.

Organ System Toxicity

May cause organ damage and disease.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Irritant

May cause skin, eye, or respiratory irritation.

Banned/restricted lists:

  • California Proposition 65 - OEHHA - developmental

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox). California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.