Methyl Isobutyl Ketone (MIBK)

Synonyms: MIBK

CAS Number: 108-10-1

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Personal care

Cleaning products and household care

Industrial uses

Arts & crafts

Description:

Methyl isobutyl ketone is an organic solvent (a ketone). It is used to help dissolve and blend ingredients and can be used as an alcohol denaturant. It is also widely used as a solvent in industrial applications.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Developmental Toxicity

May impact fetal development and birth outcomes.

Neurotoxicity

May impact brain function or development.

Organ System Toxicity

May cause organ damage and disease.

Irritant

May cause skin, eye, or respiratory irritation.

Banned/restricted lists:

European Commission Annex II prohibited substances.

References

US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.