Methylene Chloride
Synonyms: Dichloromethane
CAS Number: 75-09-2
Sources of exposure:
Historical paint strippers, adhesive removers, industrial degreasers, manufacturing solvents, and contaminated indoor air
Description:
Methylene chloride, also known as dichloromethane, is a volatile chlorinated solvent used in chemical manufacturing and industrial processing. It was historically used in consumer paint-removal and cleaning products, although many applications have been restricted or prohibited. Exposure occurs primarily through inhalation of vapors or skin contact with solvent-containing materials.
Health concerns:
Cancer
Known or suspected to increase cancer risk in humans.
Developmental Toxicity
May impact fetal development and birth outcomes.
Genotoxicity
May cause mutations or damage DNA in cells.
Neurotoxicity
May impact brain function or development.
Respiratory Toxicity & Asthmagens
May damage the lungs or trigger asthma.
Irritant
May cause skin, eye, or respiratory irritation.
Ecotoxicity
May be toxic to ecosystems and wildlife.
Banned/restricted lists:
- California Proposition 65 - OEHHA - cancer
- EU Cosmetics Regulation Annex II - Prohibited
- Health Canada Cosmetic Ingredient Hotlist - Restricted
- REACH Annex XVII - Restrictions - Restricted under specified conditions
References
- US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
- California Department of Public Health. California Safe Cosmetics Reportable Ingredients List. US National Library of Medicine. PubChem database.