N-MeFOSAA

Synonyms: 2-(N-Methylperfluorooctanesulfonamido)acetic acid

CAS Number: 2355-31-9

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
69

Sources of exposure:

Stain-resistant carpets and textiles; surface treatments; food packaging; household dust; contaminated food and water

Description:

N-MeFOSAA is a per- and polyfluoroalkyl substance (PFAS) associated with older PFOS-based stain-, grease-, and water-resistant treatments. It may be released from treated carpets, textiles, upholstery, food-contact materials, and other consumer products or formed through the breakdown of related precursor chemicals. N-MeFOSAA is environmentally persistent and can transform into PFOS, a highly persistent and bioaccumulative PFAS with well-documented health concerns. The health effects of N-MeFOSAA itself have not been studied as extensively as those of PFOS. Because this PFAS is environmentally persistent and may contribute to sustained human or ecological exposure directly or through transformation products, the glossary applies a precautionary approach where long-term hazard and exposure information is limited.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Organ System Toxicity

May cause organ damage and disease.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • EU POPs Regulation-PFOS-related compounds
  • Minnesota Amara's Law

References

  1. US National Library of Medicine. PubChem database. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).

HOW MILLION MARKER SCORES CHEMICALS

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We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.