Nitrapyrin

CAS Number: 1929-82-4

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
54

Sources of exposure:

Pesticides

Agricultural nitrogen stabilizers, fertilizer formulations, treated agricultural soil, application drift, and environmental runoff

Description:

Nitrapyrin is a synthetic nitrification inhibitor added to certain nitrogen fertilizers to slow the conversion of ammonium to nitrate in soil. It is used to improve nitrogen retention and reduce nutrient losses in agricultural systems. Exposure may occur during fertilizer handling and application or through environmental releases associated with treated agricultural land.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Developmental Toxicity

May impact fetal development and birth outcomes.

Organ System Toxicity

May cause organ damage and disease.

Immunotoxicity & Allergens

May impact immune system function or cause allergic reactions.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • California Proposition 65 - OEHHA - cancer
  • California Proposition 65 - OEHHA - developmental

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
  2. US National Library of Medicine. PubChem database.

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Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.

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