Nonoxynol-9

CAS Number: 14409-72-4

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Cleaning products and household care

Medication

Description:

Nonoxynol-9 is a nonionic surfactant used as a cleansing and emulsifying agent. It is also used as a spermicidal active ingredient in some over-the-counter contraceptive products.

Health concerns:

Endocrine Disruption

May alter hormone function and contribute to chronic diseases and disorders.

Genotoxicity

May cause mutations or damage DNA in cells.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

References

US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
California Department of Public Health. California Safe Cosmetics Reportable Ingredients List. US National Library of Medicine. PubChem database.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.