o-Phenylphenol

Synonyms: Ortho-phenylphenol, OPP

CAS Number: 90-43-7

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
71

Sources of exposure:

Personal care
Cleaning products and household care
Industrial uses
Pesticides

Disinfectants, antimicrobial cleaning products, treated citrus fruits, food-contact surfaces

Description:

o-Phenylphenol is an aromatic compound used as a disinfectant, fungicide, and antimicrobial preservative. It is used in certain cleaning and disinfecting products and has been used as a postharvest treatment to prevent fungal growth on citrus fruits. Potential exposure may occur through treated surfaces, disinfectant products, or residues on treated produce.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Genotoxicity

May cause mutations or damage DNA in cells.

Organ System Toxicity

May cause organ damage and disease.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • California Proposition 65 - OEHHA - cancer
  • EU Cosmetics Regulation Annex V - Permitted preservative

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).

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We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.

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