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p-Cresol

CAS Number: 106-44-5

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
52

Sources of exposure:

Personal care
Cleaning products and household care
Industrial uses

Environmental pollution (tobacco smoke, wood smoke, vehicle exhaust)

Description:

p-Cresol is an aromatic phenolic compound. It can be used in low amounts as a preservative or fragrance ingredient in some products and is also used in industrial applications. p-Cresol can be released into the air as a byproduct of combustion.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Developmental Toxicity

May impact fetal development and birth outcomes.

Genotoxicity

May cause mutations or damage DNA in cells.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • International Fragrance Association (IFRA) Standards for maximum concentrations in finished products. Government of Canada. List of Ingredients that are Prohibited for Use in Cosmetic Products.

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
  2. California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.
  3. US National Library of Medicine. PubChem database.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.

For more information on our scoring methodology visit this page.