para-Dichlorobenzene

Synonyms: 1,4-Dichlorobenzene, p-Dichlorobenzene

CAS Number: 106-46-7

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
37

Sources of exposure:

Industrial uses
Pesticides
Cleaning products and household care

Mothballs, moth repellents, toilet deodorizer blocks, older air fresheners, chemical manufacturing, and indoor air

Description:

para-Dichlorobenzene, also known as 1,4-dichlorobenzene, is a chlorinated aromatic compound used in certain moth repellents and deodorizing products. It readily evaporates into air, making inhalation an important exposure pathway. It is also used as a chemical intermediate in industrial manufacturing.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Genotoxicity

May cause mutations or damage DNA in cells.

Neurotoxicity

May impact brain function or development.

Organ System Toxicity

May cause organ damage and disease.

Immunotoxicity & Allergens

May impact immune system function or cause allergic reactions.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • California Proposition 65 - OEHHA - cancer
  • EU Cosmetics Regulation Annex II - Prohibited
  • REACH Annex XVII - Restrictions - Restricted under specified conditions

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
  2. California Department of Public Health. California Safe Cosmetics Reportable Ingredients List. US National Library of Medicine. PubChem database.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.