Pentachlorophenol
CAS Number: 87-86-5
Sources of exposure:
Historically treated utility poles, railroad ties, industrial wood preservatives, contaminated soil, groundwater, and contact with treated wood
Description:
Pentachlorophenol is a chlorinated phenolic compound historically used as a pesticide and industrial wood preservative to protect wood from fungi and insects. Its use has been phased out or prohibited in many jurisdictions, including the United States. Exposure may still occur through historically treated wood, contaminated soil, or groundwater.
Health concerns:
Cancer
Known or suspected to increase cancer risk in humans.
Endocrine Disruption
May alter hormone function and contribute to chronic diseases and disorders.
Neurotoxicity
May impact brain function or development.
Organ System Toxicity
May cause organ damage and disease.
Immunotoxicity & Allergens
May impact immune system function or cause allergic reactions.
Respiratory Toxicity & Asthmagens
May damage the lungs or trigger asthma.
Irritant
May cause skin, eye, or respiratory irritation.
Ecotoxicity
May be toxic to ecosystems and wildlife.
Banned/restricted lists:
- California Proposition 65 - OEHHA - cancer
- EU Cosmetics Regulation Annex II - Prohibited
- Rotterdam Convention - Annex III - Prior Informed Consent (PIC) - Pesticide
References
- US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox). California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.