Permethrin

CAS Number: 52645-53-1

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
22

Sources of exposure:

Pesticides
Personal care
Medications
Food

Household insecticides, mosquito-control applications, insect-treated clothing, head-lice treatments, scabies medications, agricultural applications, and potential food residues

Description:

Permethrin is a synthetic pyrethroid insecticide used to control a variety of insects. It is found in agricultural and household pest-control products, insect-treated clothing, and certain topical medications used to treat head lice and scabies. Exposure may occur through contact with treated surfaces or clothing, use of pest-control products, medical treatments, or residues on food.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Endocrine Disruption

May alter hormone function and contribute to chronic diseases and disorders.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Developmental Toxicity

May impact fetal development and birth outcomes.

Neurotoxicity

May impact brain function or development.

Immunotoxicity & Allergens

May impact immune system function or cause allergic reactions.

Ecotoxicity

May be toxic to ecosystems and wildlife.

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox). California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.