PFAS (Per- and Polyfluoroalkyl Substances)

Sources of exposure:

Personal care
Industrial uses
Food

Drinking water, food packaging, nonstick cookware, stain-resistant textiles, carpets, cosmetics, firefighting foams, household dust

Description:

Per- and polyfluoroalkyl substances (PFAS) are a large and diverse class of synthetic organofluorine chemicals used in industrial processes and consumer products. Many PFAS have properties that make them useful for resisting water, oil, grease, and stains, and they have been used in food packaging, textiles, nonstick coatings, cosmetics, and firefighting foams. Human exposure can occur through contaminated drinking water and food, household dust, and contact with certain consumer products. PFAS vary considerably in their chemical structures, uses, environmental behavior, and potential health effects. Many are highly persistent in the environment, while some can accumulate in humans and wildlife. Although certain PFAS have been extensively studied, substantial information gaps remain for many substances in this class. Examples include perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS), perfluorohexanesulfonic acid (PFHxS), and fluoropolymers such as polytetrafluoroethylene (PTFE). Per- and polyfluoroalkyl substances (PFAS) are subject to a growing number of international and national regulations. Specific PFAS, including PFOA, PFOS, and PFHxS, are listed under the Stockholm Convention on Persistent Organic Pollutants and are restricted under the European Union's Persistent Organic Pollutants Regulation (EU) 2019/1021. Additional PFAS substances and uses are restricted under the EU REACH Regulation, including certain perfluorocarboxylic acids and PFAS in firefighting foams. In the United States, the Environmental Protection Agency has established enforceable drinking water standards for certain PFAS, including PFOA and PFOS. These regulations apply to specific substances, chemical subgroups, or uses rather than all PFAS universally.

Health concerns:

No specific health concerns have been flagged for this chemical.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.