PFDA

Synonyms: Perfluorodecanoic Acid

CAS Number: 335-76-2

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

75

Sources of exposure:

Contaminated food and water; fluorochemical manufacturing; stain-resistant products; household dust

Description:

PFDA is a long-chain per- and polyfluoroalkyl substance (PFAS) associated with fluorochemical manufacturing, industrial processing, and the breakdown of precursor PFAS used in treated textiles, coatings, and other products. Exposure may occur through contaminated food and water, household dust, industrial emissions, and contact with PFAS-treated materials. PFDA is extremely persistent and bioaccumulative and may remain in the body for an extended period. Because this PFAS is environmentally persistent and may remain mobile or bioaccumulative depending on its structure and exposure setting, the glossary applies a precautionary approach where long-term hazard and exposure information is limited.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Developmental Toxicity

May impact fetal development and birth outcomes.

Irritant

May cause skin, eye, or respiratory irritation.

Banned/restricted lists:

EU REACH Annex XVII-C9-C14 PFCAs
Canada Prohibition of Certain Toxic Substances Regulations
Minnesota Amara's Law

References

California Department of Public Health. California Safe Cosmetics Reportable Ingredients List. US National Library of Medicine. PubChem database.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.