PFOS

Synonyms: Perfluorooctanesulfonic acid

CAS Number: 1763-23-1

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
29

Sources of exposure:

Cleaning products and household care
industrial uses

Environmental pollution (soil, water), consumer goods, packaging, fire fighting foam, consumer goods, stain and water repellent products

Description:

PFOS is a perfluorinated compound (PFAS). It is a persistent environmental contaminant historically used in consumer products such as carpets, clothing, paper and cardboard food packaging, and firefighting foams. PFOS can also form as a degradation product of other PFAS. Its use is restricted or banned under multiple regulatory frameworks, including the Stockholm Convention (Annex B), US EPA TSCA, US Safe Drinking Water Act, and the EU POPs Regulation.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Endocrine Disruption

May alter hormone function and contribute to chronic diseases and disorders.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Developmental Toxicity

May impact fetal development and birth outcomes.

Genotoxicity

May cause mutations or damage DNA in cells.

Organ System Toxicity

May cause organ damage and disease.

Immunotoxicity & Allergens

May impact immune system function or cause allergic reactions.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • Stockholm Convention on Persistent Organic Pollutants (POPs)

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.