Poloxamer 184

CAS Number: 9003-11-6

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Personal care

Medications

Description:

Poloxamer 184 is an ethoxylated nonionic surfactant used in cosmetics, personal care products, and pharmaceuticals to help solubilize and stabilize formulations. As an ethoxylated chemical, its manufacturing process may result in contamination with 1,4-dioxane.

Health concerns:

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Contaminants:

1
4-dioxane

References

US National Library of Medicine. PubChem database.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.