Propoxur

CAS Number: 114-26-1

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
57

Sources of exposure:

Pesticides

Historical household insecticides, cockroach and ant control products, treated indoor surfaces, older pest-control formulations, and contaminated indoor dust

Description:

Propoxur is a carbamate insecticide historically used to control cockroaches, ants, and other household or agricultural pests. It acts by inhibiting acetylcholinesterase, an enzyme involved in nerve signaling. Many uses have been discontinued or restricted in the United States. Exposure may occur through older pest-control products, contaminated indoor environments, or applications in jurisdictions where use remains permitted.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Neurotoxicity

May impact brain function or development.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • California Proposition 65 - OEHHA - cancer

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox). California Department of Public Health. California Safe Cosmetics Reportable Ingredients List.

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We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.

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