Rotenone

CAS Number: 83-79-4

Sources of exposure:

Pesticides; environmental contamination (treated lakes and waterways)

Description:

Rotenone is a naturally occurring insecticidal compound derived from the roots of several tropical plant species. Most U.S. food-crop and other conventional insecticidal uses have been discontinued. Current U.S. pesticidal registrations are restricted-use products for trained applicators to manage invasive or unwanted fish populations in water bodies. Rotenone is not approved as an active substance for plant-protection products in the European Union.

Health concerns:

Organ System Toxicity

May cause organ damage and disease.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

PAN International Highly Hazardous Pesticides (HHP) List

References

US National Library of Medicine. PubChem database.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.