Tetrahydropiperine

CAS Number: 23434-88-0

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Personal care

Skin care products, cosmetic serums, topical formulations, and products containing penetration-enhancing ingredients

Description:

Tetrahydropiperine is a hydrogenated derivative of piperine, a naturally occurring compound found in black pepper. It is used in certain cosmetic and skin care formulations as a penetration enhancer to help improve the delivery of other ingredients through the skin.

Health concerns:

Low Health Concerns

Current research suggests ingredient may be safe for use.

References

US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.