Thiophanate-methyl

CAS Number: 23564-05-8

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Food

Agricultural fungicides; treated seeds; turf and ornamental plants; occupational pesticide use

Description:

Thiophanate-methyl is a systemic fungicide used on fruits, vegetables, grains, nuts, seeds, turf, and ornamental plants. It breaks down into carbendazim, a generally more environmentally persistent fungicidal compound. Thiophanate-methyl remains registered for specified uses in the United States with measures intended to reduce dietary, occupational, and ecological exposure, but its approval was not renewed in the European Union.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Genotoxicity

May cause mutations or damage DNA in cells.

Immunotoxicity & Allergens

May impact immune system function or cause allergic reactions.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

PAN International Highly Hazardous Pesticides (HHP) List

References

California Department of Public Health. California Safe Cosmetics Reportable Ingredients List. US National Library of Medicine. PubChem database.

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.