Titanium Dioxide

Synonyms: CI 77891, C.I. Pigment White 6

CAS Number: 13463-67-7

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Personal care

Cleaning products and household care

Food

Medication

Industrial uses

Home goods, plastic, paint

Description:

Titanium dioxide is an inorganic metal oxide pigment. It is used as a physical UV filter in sunscreens and as a white colorant in cosmetics, foods, and medications. Titanium dioxide is a potential occupational carcinogen, especially when inhaled in the nanoparticle form.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Genotoxicity

May cause mutations or damage DNA in cells.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

European Commission Annex III restrictions. European Commission Annex VI UV filters allowed in cosmetic products. European Commission Annex IV colorants allowed in cosmetic products.

References

US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.