Toxaphene

CAS Number: 8001-35-2

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79
80 89
90 100
54

Sources of exposure:

Food
Pesticides

Environmental pollution (soil and water)

Description:

Toxaphene is a complex mixture of chlorinated chemicals formerly used as an agricultural insecticide. It is classified as a Persistent Organic Pollutant (POP) under the Stockholm Convention and is effectively banned and prohibited for use internationally.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Neurotoxicity

May impact brain function or development.

Organ System Toxicity

May cause organ damage and disease.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Irritant

May cause skin, eye, or respiratory irritation.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Banned/restricted lists:

  • EU Cosmetics Regulation Annex II - Prohibited
  • California Proposition 65 - OEHHA - cancer
  • Stockholm Convention on Persistent Organic Pollutants - Annex A - Elimination
  • Rotterdam Convention - Annex III - Prior Informed Consent (PIC) - Pesticide

References

  1. US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox). California Department of Public Health. California Safe Cosmetics Reportable Ingredients List. UN Environment Programme. Stockholm Convention on Persistent Organic Pollutants (POPs).

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We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.

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