Warfarin
CAS Number: 81-81-2
Sources of exposure:
Prescription anticoagulant medications, historical and some currently authorized rodenticides, pest-control baits, and accidental contact with rodent-control products
Description:
Warfarin is a synthetic anticoagulant used as a prescription medication to prevent or treat blood clots. It has also been used as a rodenticide because it interferes with vitamin K-dependent blood clotting. Exposure may occur through prescribed medication or contact with rodent-control products containing warfarin.
Health concerns:
Reproductive Toxicity
May alter hormone function and harm reproduction.
Developmental Toxicity
May impact fetal development and birth outcomes.
Genotoxicity
May cause mutations or damage DNA in cells.
Organ System Toxicity
May cause organ damage and disease.
Irritant
May cause skin, eye, or respiratory irritation.
Ecotoxicity
May be toxic to ecosystems and wildlife.
Banned/restricted lists:
- California Proposition 65 - OEHHA - developmental
- EU Cosmetics Regulation Annex II - Prohibited
- Health Canada Cosmetic Ingredient Hotlist - Prohibited
References
- US Environmental Protection Agency. Cheminformatics Modules, Computational Toxicology and Exposure Informatics (CompTox).
- California Department of Public Health. California Safe Cosmetics Reportable Ingredients List. US National Library of Medicine. PubChem database.